Red wine: FODMAP, histamine, lactose and gluten

Here is what the scientific sources say about Red wine for people managing sensitivities to FODMAP, histamine, gluten and lactose.

Histamine

The histamine/biogenic amine content of Red wine is considered medium (0-3 intensity scale).

Sources: Esposito F, Montuori P, Schettino M, Velotto S, Stasi T, Romano R, Cirillo T (2019). 'Level of Biogenic Amines in Red and White Wines, Dietary Exposure, and Histamine-Mediated Symptoms upon Wine Ingestion.' Molecules 24(19):3629. doi:10.3390/molecules24193629

LTP (lipid transfer protein)

The LTP risk associated with Red wine is classified as high.

Sources: Pastorello EA, et al. 2003. Identification of grape and wine allergens as an endochitinase 4, a lipid-transfer protein, and a thaumatin. J Allergy Clin Immunol 111(2):350-359 (PMID 12589356) — identifica Vit v 1 (LTP, 9 kDa, registrata WHO/IUIS con esposizione alimentare) come allergene maggiore di uva e vino, responsabile anche di anafilassi. Wigand P, Tenzer S, Schild H, Decker H. 2009. J Agric Food Chem 57(10):4328-4333 (PMID 19385597) — la LTP è presente in quantità nettamente maggiori nei vini rossi (es. Dornfelder) rispetto a rosé e bianchi, per il contatto prolungato con le bucce durante la macerazione; l'alcol/vino è inoltre un noto cofattore/augmentation factor nelle reazioni da sindrome LTP.

Lactose and gluten

Lactose is not naturally present in Red wine. Gluten is not naturally present in Red wine.

Frequently asked questions

What is the histamine content of Red wine?
The histamine content of Red wine is medium, according to the cited source.
What is the LTP risk of Red wine for sensitive people?
The LTP risk of Red wine is high, according to the cited source.
Is lactose naturally present in Red wine?
No, lactose is not naturally present in Red wine.
Is gluten naturally present in Red wine?
No, gluten is not naturally present in Red wine.

[draft pending legal review] This service does not provide medical advice and does not replace the opinion of a healthcare professional. It is not designed to handle anaphylactic reactions: in an emergency, contact emergency services immediately. You can declare, in free text, the substances you're allergic or intolerant to: an AI interprets them and the app tries to exclude them from scanner results, recipes, and products. This is a best-effort aid to reduce risk, not a safety guarantee: the underlying ingredient and product data isn't clinically validated allergen by allergen, and your declaration may be interpreted inaccurately. Always check the label yourself before consuming a product, especially for severe allergies.

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